Antioxidant Medications: Beware of Toxicity from Overconsumption
In the past decade, a plethora of antioxidant medications has emerged, promising anti-aging benefits. However, recent reports indicate a rise in cases of adverse side effects linked to the excessive and prolonged use of these drugs. Hence, it is crucial to be vigilant about the potential toxicity of certain antioxidant medications when consumed in high doses or over an extended period.
Vitamin E (Tocopherol)
Taking high doses of Vitamin E (over 100 mg daily) for an extended period can lead to various non-specific discomforts. If used for more than six months, there is a heightened risk of platelet aggregation and thrombosis. When the dosage exceeds 400 mg per day for more than a year, especially in combination with estrogen, the likelihood of developing thrombotic venous inflammation significantly increases.
Vitamin C
Consuming large quantities of Vitamin C can cause digestive issues, such as diarrhea, and may result in the precipitation of cystine in the urinary tract or the formation of oxalate stones.
Penicillamine
Long-term use of Penicillamine may stimulate kidney irritation and lead to leukopenia, a reduction in white blood cells.
Excess Trace Elements
While trace elements are essential for health, excessive intake can lead to harmful effects. For instance, high levels of zinc can cause nausea, vomiting, and diarrhea, while excess cobalt is toxic to the myocardium and may result in heart failure and death. Overconsumption of selenium can cause hair loss, nail abnormalities, and skin discoloration. Selenium toxicity may also lead to gastrointestinal disturbances, dizziness, impotence, fatigue, irritability, and depressive symptoms. Animal studies suggest that selenium can cause embryonic deformities, and an excess of iron can adversely affect the pancreas and gonads.
Traditional Chinese Anti-Aging Herbs
Although many traditional Chinese remedies are celebrated for their low toxicity, misuse can have adverse effects. For example, while ginseng is renowned for its anti-aging properties, taking excessive amounts (3 grams or more daily) can induce “ginseng abuse syndrome.” In newborns, a dosage of 0.6 to 0.9 grams can result in toxicity. Additionally, injectable forms of deer antler essence may cause skin rashes, allergic shock, acute cardiogenic cerebral hypoxia syndrome, heart palpitations, vomiting, nausea, and abdominal pain. Danshen injection can lead to heavy menstrual bleeding, fatigue, drowsiness, headaches, and bleeding from the nasal mucosa and gums.
Honey and Other Herbal Compounds
Though honey is traditionally associated with longevity, toxicity incidents have been reported. Furthermore, consuming Fo-Ti may result in paroxysmal convulsions, restlessness, and even respiratory paralysis. Some combination formulas with anti-aging herbs should also be approached with caution. For example, taking excess Shuangbao Su, which contains ginseng and bee pollen, can lead to extreme central nervous system excitation, potentially resulting in manic episodes. Moreover, Liuwei Dihuang Wan may induce urticarial drug rashes, while traditional formulas like Shenrong Weisheng Wan contain vermilion, leading to mercury poisoning when used repeatedly.
Conclusion
In summary, while antioxidant medications and traditional herbal remedies can offer various health benefits, caution is paramount in their usage. Overconsumption can lead to serious health risks, including toxicity. Always consult healthcare professionals before starting any new treatment regimen to ensure safety and effectiveness.